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2010

 

1. Albanese A, Asmus F, Bhatia KP, Elia AE, Elibol B, Filippini G, Gasser T, Krauss JK, Nardocci N, Newton A, Valls-Solé J (2010). EFNS guidelines on diagnosis and treatment of primary dystonias. Eur J Neurol. 18 (1), 5-18.

 

2. Albayrak O, Tirniceriu A, Riemenschneider M, Kurz A, Scherag A, Egensperger R (2010). The cathepsin D (224C/T) polymorphism confers an increased risk to develop Alzheimer's disease in men. J Gerontol A Biol Sci Med Sci. 65 (3), 219-24.

 

3. Andersen OS, Boisguerin P, Glerup S, Skeldal S, Volkmer R, Willnow TE, Nykjaer A, Andersen OM (2010). Identification of a linear epitope in sortilin that partakes in pro-neurotrophin binding. J. Biol. Chem. 285, 12210-22.

 

4. Aron L, Klein P, Pham TT, Kramer ER, Wurst W, Klein R (2010). Pro-survival role for Parkinson's associated gene DJ-1 revealed in trophically impaired dopaminergic neurons. PLoS Biol. 8(4), e1000349 epub ahead of print.

 

5. Asmus F, Gasser T (2010). Dystonia-plus syndromes. Eur J Neurol. Suppl 1, 37-45.

 

6. Augustin R, Lichtenthaler SF, Hansen J, Greeff M, Wurst W, Trümbach D (2010). Bioinformatics identification of modules of transcription factor binding sites in Alzheimer’s Disease related genes by in silico promoter analysis and microarrays, submitted to: Int J Alzheimers Dis.

 

7. Beckervordersandforth R, Tripathi P, Ninkovic J, Bayam E, Lepier A, Stempfhuber B, Kirchhoff F, Hirrlinger J, Haslinger A, Lie DC, Beckers J, Yoder B, Irmler M, Götz M. (2010). In vivo fate mapping and expression analysis reveals molecular hallmarks of prospectively isolated adult neural stem cells. Cell Stem Cell. 2010 Dec 3;7(6):744-58

 

8. Berg D, Seppi K, Liepelt I, Schweitzer K, Wollenweber F, Wolf B, Dillmann U, Stockner H, Godau J, Kiechl S, Gaenslen A, Willeit J, Di Santo A, Maetzler W, Gasser T, Poewe W, Behnke S (2010). Enlarged hyperechogenic substantia nigra is related to motor performance and olfaction in the elderly. Mov Disord. 25 (10), 1464-9.

 

9. Bieschke J, Russ J, Friedrich RP, Ehrnhoefer DE, Wobst H, Neugebauer K, Wanker EE (2010). EGCG remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity. Proc Natl Acad Sci USA 107 (17), 7710-5.

 

10. Birchmeier C (2010). Development and more. Semin Cell Dev Biol. 21 (8), 812-3.

 

11. Blauw HM, Al-Chalabi A, Andersen PM, van Vught PW, Diekstra FP, van Es MA, Saris CG, Groen EJ, van Rheenen W, Koppers M, Van't Slot R, Strengman E, Estrada K, Rivadeneira F, Hofman A, Uitterlinden AG, Kiemeney LA, Vermeulen SH, Birve A, Waibel S, Meyer T, Cronin S, McLaughlin RL, Hardiman O, Sapp PC, Tobin MD, Wain LV, Tomik B, Slowik A, Lemmens R, Rujescu D, Schulte C, Gasser T, Brown RH Jr, Landers JE, Robberecht W, Ludolph AC, Ophoff RA, Veldink JH, van den Berg LH (2010). A large genome scan for rare CNVs in amyotrophic lateral sclerosis. Submitted to Hum Mol Genet.

 

12. Blum R, Heinrich C, Sanchez R, Lepier A, Gundelfinger ED, Berninger B, Götz M (2010). Neuronal network formation from reprogrammed rat cortical glial cells. Cerebral cortex Jun 24, doi: 10.1093/cercor/bhq107.

 

13. Bouman L, Schlierf A, Lutz AK, Shan J, Deinlein A, Kast J, Galehdar Z, Palmisano V, Patenge N, Berg D, Gasser T, Augustin R, Trümbach D, Irrcher I, Park D, Wurst W, Kilberg MS, Tatzelt J, Winklhofer KF (2010). Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress. Cell Death Differ, epub doi, 10.1038/cdd.2010.142.

 

14. Breit S, Wachter T, Schmid-Bielenberg D, Weiss D, Leitner P, Nagele T, Freudenstein D, Gasser T, Kruger R (2010). Effective long-term subthalamic stimulation in PARK8 positive Parkinson's disease. J Neurol. 257 (7), 1205-7.

 

15. Brockmann K, Gasser T (2010). Genetic basis of monogenic forms of Parkinson’s Disease. Encyclopedia of Life Sciences, April 19, 2010.

 

16. Burgunder JM, Finsterer J, Szolnoki Z, Fontaine B, Baets J, Van Broeckhoven C, Di Donato S, De Jonghe P, Lynch T, Mariotti C, Schols L, Spinazzola A, Tabrizi SJ, Tallaksen C, Zeviani M, Harbo HF, Gasser T (2010). EFNS guidelines on the molecular diagnosis of channelopathies, epilepsies, migraine, stroke, and dementias. Eur J Neurol. 17 (5), 641-8.

 

17. Burgunder JM, Schöls L, Baets J, Andersen P, Gasser T, Szolnoki Z, Fontaine B, Van Broeckhoven C, Di Donato S, De Jonghe P, Lynch T, Mariotti C, Spinazzola A, Tabrizi SJ, Tallaksen C, Zeviani M, Harbo HF, Finsterer J (2010). EFNS guidelines for the molecular diagnosis of neurogenetic disorders: motoneuron, peripheral nerve and muscle disorders. Eur J Neurol. 17 (5), 641-8.

 

18. Carballo-Carbajal I, Weber-Endress S, Rovelli G, Chan D, Wolozin B, Klein CL, Patenge N, Gasser T, Kahle PJ (2010). Leucine-rich repeat kinase 2 induces alpha-synuclein expression via the extracellular signal-regulated kinase pathway. Cell Signal 22, 821-827.

 

19. Caspers SV, Zilles K, Laird AR, Eickhoff SB (2010). ALE meta-analysis of action observation and imitation in the human brain. NeuroImage 50: 1148-1167.

 

20. Castelo-Branco G, Andersson ER, Minina E, Sousa KM, Ribeiro D, Kokubu C, Imai K, Prakash N, Wurst W, Arenas E (2010). Delayed dopaminergic neuron differentiation in Lrp6 mutant mice. Dev Dyn. 239 (1), 211-21.

 

21. Cox BJ, Vollmer M, Tamplin O, Lu M, Biechele S, Gertsenstein M, van Campenhout C, Floss T, Kühn R, Wurst W, Lickert H, Rossant J (2010). Phenotypic annotation of the mouse X chromosome. Genome Res.8, 1154-64.

 

22. Cremer CM, Bidmon H-J, Görg B, Palomero-Gallagher N, Lopez Escobar J, Speckmann E-J, Zilles K (2010). Inhibition of glutamate/glutamine cycle in vivo results in decreased benzodiazepine binding and differentially regulated GABAergic subunit expression in the rat brain. Epilepsia epub doi, 10.1111/j.1528-1167.2010.02562.x.

 

23. Deussing JM, Breu J, Kühne C, Kallnik M, Bunck M, Glasl L, Yen YC, Schmidt MV, Zurmühlen R, Vogl AM, Gailus-Durner V, Fuchs H, Hölter SM, Wotjak CT, Landgraf R, de Angelis MH, Holsboer F, Wurst W (2010). Urocortin 3 modulates social discrimination abilities via corticotropin-releasing hormone receptor type 2. J. Neurosci. 30, 9103-9116.

 

24. Di Salvio M, Di Giovannantonio LG, Acampora D, Prosperi R, Omodei D, Prakash N, Wurst W, Simeone A (2010). Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP. Nat Neurosci. 13 (12), 1481-8.

 

25. Dodel R, Spottke A, Gerhard A, Reuss A, Reinecker S, Schimke N, Trenkwalder C, Sixel-Doring F, Herting B, Kamm C, Gasser T, Sawires M, Geser F, Kollensperger M, Seppi K, Kloss M, Krause M, Daniels C, Deuschl G, Bottger S, Naumann M, Lipp A, Gruber D, Kupsch A, Du Y, Turkheimer F, Brooks DJ, Klockgether T, Poewe W, Wenning G, Schade-Brittinger C, Oertel WH, Eggert K (2010). Minocycline 1-year therapy in multiple-system-atrophy: effect on clinical symptoms and [(11)C] (R)-PK11195 PET (MEMSA-trial). Mov Disord. 25 (1), 97-107.

 

26. Ehm O, Göritz C, Covic M, Schäffner I, Schwarz TJ, Karaca E, Kempkes B, Kremmer E, Pfrieger FW, Espinosa L, Bigas A, Giachino C, Taylor V, Frisén J, Lie DC (2010). RBPJkappa-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus. J Neurosci. 30 (41), 13794-807.

 

27. Eickhoff SB, Pomjanski W, Jakobs O, Zilles K, Langner R (2010). Neural correlates of developing and adapting behavioural biases in speeded choice reactions – An fMRI study on predictive motor coding. Cerebral Cortex epub doi, 10.1093/cercor/bhq188.

 

28. Elzer JG, Muhammad S, Wintermantel TM, Regnier-Vigouroux A, Schütz G, Schwaninger M (2010). Neuronal estrogen receptor-alpha mediates neuroprotection by 17b-estradiol. J. Cereb. Blood Flow Metab. 30, 935-942.

 

29. Enokido Y, Tamura T, Ito H, Arumughan A, Komuro A, Shiwaku H, Sone M, Foulle R, Sawada H, Ishiguro H, Ono T, Murata M, Kanazawa I, Tomilin N, Tagawa K, Wanker EE, Okazawa H (2010). Mutant huntingtin impairs Ku70-mediated DNA repair. J Cell Biol. 189 (3), 425-43.

 

30. Evangelou E, Maraganore DM, Annesi G, Brighina L, Brice A, Elbaz A, Ferrarese C, Hadjigeorgiou GM, Krueger R, Lambert JC, Lesage S, Markopoulou K, Mellick GD, Meeus B, Pedersen NL, Quattrone A, Van Broeckhoven C, Sharma M, Silburn PA, Tan EK, Wirdefeldt K, Ioannidis JP (2010). Genetic Epidemiology of Parkinson's Disease (GEOPD) Consortium. Non-replication of association for six polymorphisms from meta-analysis of genome-wide association studies of Parkinson's disease: large-scale collaborative study. Am J Med Genet B Neuropsychiatr Genet. 153B (1), 220-8.

 

31. Fassler M, Zocher M, Klare S, de la Fuente AG, Scheuermann J, Capell A, Haass C, Valkova C, Veerappan A, Schneider D, Kaether C (2010). Masking of transmembrane-based retention signals controls ER export of gamma-secretase. Traffic 11 (2), 250-8.

 

32. Fett ME, Pilsl A, Paquet D, Haass C, Tatzelt J, Schmid B, Winklhofer KF (2010). Parkin is protective against proteotoxic stress in a transgenic zebrafish model. PLoS One 5 (7), e11783.

 

33. Fiesel FC, Voigt A, Weber SS, Van den Haute C, Waldenmaier A, Görner K, Walter M, Anderson ML, Kern JV, Rasse TM, Schmidt T, Springer W, Kirchner R, Bonin M, Neumann M, Baekelandt V, Alunni-Fabbroni M, Schulz JB, Kahle PJ (2010). Knockdown of transactive response DNA-binding protein TDP-43 downregulates histone deacetylase 6. EMBO J. 29, 209-221.

 

34. Fischer T, Faus-Kessler T, Welzl G, McWhirter JR, Mansour SL, Goetz M, Murre C, Wurst W, Prakash N (2010). Fgf15-Mediated Control of Proneural and Neurogenic Gene Expression Regulates Dorsal Midbrain Neurogenesis Fgf15 is a Neurogenic Signal for the Mouse Dorsal Midbrain. Development (accepted).

 

35. Fuchs H, Gailus-Durner V, Adler T, Aguilar-Pimentel JA, Becker L, Calzada-Wack J, Da Silva-Buttkus P, Neff F, Götz A, Hans W, Hölter SM, Horsch M, Kastenmüller G, Kemter E, Lengger C, Maier H, Matloka M, Möller G, Naton B, Prehn C, Puk O, Rácz I, Rathkolb B, Römisch-Margl W, Rozman J, Wang-Sattler R, Schrewe A, Stöger C, Tost M, Adamski J, Aigner B, Beckers J, Behrendt H, Busch DH, Esposito I, Graw J, Illig T, Ivandic B, Klingenspor M, Klopstock T, Kremmer E, Mempel M, Neschen S, Ollert M, Schulz H, Suhre K, Wolf E, Wurst W, Zimmer A, Hrabé de Angelis M (2010). Mouse Phenotyping. Methods, Aug 12 doi:10.1016/j.ymeth.2010.08.006.

 

36. Gasser T (2010). PARK3. Encyclopedia of Movement Disorders, 3, 386-187.

 

37. Gasser T, Finsterer J, Baets J, Van Broeckhoven C, Di Donato S, Fontaine B, De Jonghe P, Lossos A, Lynch T, Mariotti C, Schols L, Spinazzola A, Szolnoki Z, Tabrizi SJ, Tallaksen CM, Zeviani M, Burgunder JM, Harbo HF (2010). EFNS guidelines on the molecular diagnosis of ataxias and spastic paraplegias. Eur J Neurol. 17 (2), 179-88.

 

38. Gasser T (2010). Identifying PD-causing genes and genetic susceptibility factors: current approaches and future prospects. Prog Brain Res.183, 3-20.

 

39. Gerards M, van den Bosch BJ, Danhauser K, Serre V, van Weeghel M, Wanders RJ, Nicolaes GA, Sluiter W, Schoonderwoerd K, Scholte HR, Prokisch H, Röthig A, de Coo IF, Smeets HJ (2010). Riboflavin-responsive oxidative phosphorylation complex I deficiency caused by defective ACAD9: new function for an old gene. Brain 134 (Pt 1), 210-9.

 

40. Gloeckner CJ; Boldt K, von Zweydorf F, Helm S, Wiesent L, Sarioglu H, Ueffing M, (2010). Phosphopeptide Analysis reveals two discrete clusters of phosphorylation in the N-terminus and the Roc domain of the Parkinson-disease associated protein kinase LRRK2. J. Proteome. Res. 9 (4), 1738-1745.

 

41. Goehler H, Droege A, Lurz R, Schnoegl S, Chernoff Y, Wanker EE (2010). Pathogenic polyglutamine tracts are potent inducers of spontaneous Sup35 and Rnq1 amyloidogeneses. PLOS ONE 5 (3), e9642.

 

42. Graf C, Pütz B, Kühne C, Panhuysen M, Breu J, Weber P, Holsboer F, Wurst W, Deussing JM (2010). Dissecting corticotrope and neuronal corticotropin-releasing hormone receptor type 1 signaling pathways: common target genes with divergent functions Submitted Journal of Neurochemistry.

 

43. Godau J, Herfurth M, Kattner B, Gasser T, Berg D (2010). Increased serum insulin-like growth factor 1 in early idiopathic Parkinson's disease. J Neurol Neurosurg Psychiatry. 81 (5), 536-8.

 

44. Haack TB, Danhauser K, Haberberger B, Hoser J, Strecker V, Boehm D, Uziel G, Lamantea E, Invernizzi F, Poulton J, Rolinski B, Iuso A, Biskup S, Schmidt T, Mewes HW, Wittig I, Meitinger T, Zeviani M, Prokisch H (2010). Exome sequencing identifies ACAD9 mutations as a cause of complex I deficiency. Nat Genet. 42 (12), 1131-4.

 

45. Hackl C, Papazoglou A, Ganser C, Klein A, Prakash N, Wurst W, Nikkhah G (2010). Ectopic dopaminergic progenitor cells from En1+/Otx2lacZ transgenic mice survive and functionally reinnervate the striatum following transplantation in a rat model of Parkinson's disease. Cell Transplant. 19(9), 1085-101.

 

46. Haebig K, Gloeckner CJ, Miralles MG, Gillardon F, Schulte C, Riess O, Ueffing M, Bonin M (2010). ARHGEF7 (BETA-PIX) acts as guanine nucleotide exchange factor for Leucine-rich repeat kinase 2. PlosOne 5 (10), e13762.

 

47. Heinrich C, Blum R, Tripathi P, Götz M, Berninger B (2010). Directing astroglia from the cerebral cortex into functional subtype-specific neurons. PLOS Biology 8, e1000373.

 

48. Heinrich C, Gascón S, Masserdotti G, Lepier A, Sanchez R, Simon-Ebert T, Schroeder T, Götz M, Berninger B (2010). Generation of subtype specific neurons from postnatal astroglia of the mouse cerebral cortex. Nature Protocols, May 18; doi: 10.1371/journal.pbio.1000373.

 

49. Herold S, Jagasia R, Merz K, Wassmer K, Lie DC (2011). CREB signalling regulates early survival, neuronal gene expression and morphological development in adult subventricular zone neurogenesis. Mol Cell Neurosci. 46(1), 79-88.

 

50. Herzer M, Koch J, Prokisch H, Rodenburg R, Rauscher C, Radauer W, Forstner R, Pilz P, Rolinski B, Freisinger P, Mayr JA, Sperl W (2010). Leigh disease with brainstem involvement in complex I deficiency due to assembly factor NDUFAF2 defect. Neuropediatrics 41 (1), 30-4.

 

51. Hölter SM, Cryan JF (2010). Phenotyping of Behavioural Characteristics. In: Encyclopedia of Psychopharmacology, Springer-Verlag.

 

52. Irrcher I, Aleyasin H, Seifert EL, Hewitt SJ, Chhabra S, Phillips M, Lutz, AK, Rousseaux MW, Bevilacqua L, Jahani-Asl A, Callaghan S, Maclaurin JG, Winklhofer KF, Rizzu P, Rippstein P, Kim RH, Chen CX, Fon EA, Slack RS, Harper ME, McBride HM, Mak TW, Park DS (2010). Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics. Hum Mol Genet. 19, 3734-3746.

 

53. Jawerka M, Colak D, Dimou L, Spiller C, Lagger S, Montgomery RL, Olson EN, Wurst W, Göttlicher M, Götz M (2010). The specific role of histone deacetylase 2 in adult neurogenesis. Neuron Glia Biology 6, 93-107.

 

54. Kamp F, Exner N, Lutz AK, Wender N, Hegermann J, Brunner B, Nuscher B, Bartels T, Giese A, Beyer K, Eimer S, Winklhofer KF, Haass C (2010). Inhibition of Mitochondrial Fusion by a-Synuclein is rescued by PINK1, Parkin, and DJ-1. EMBO J. 29, 3571-3589.

 

55. Karst H, Berger S, Erdmann G, Schütz G, Joels M (2010). Metaplasticity in amygdalar responses to the stress hormone corticosterone. Proc. Natl. Acad. Sci. USA 107, 14449-14454.

 

56. Kimura M, Muller-Preuss P, Lu A, Wiesner E, Flachskamm C, Wurst W, Holsboer F, Deussing JM (2010). Conditional corticotropin-releasing hormone overexpression in the mouse forebrain enhances rapid eye movement sleep. Mol Psychiatry 15, 154-165.

 

57. Kjolby M, Andersen OM, Breiderhoff T, Fjorback AW, Pedersen KM, Madsen P, Jansen P, Heeren J, Willnow TE, Nykjaer A (2010). Sort1, encoded by the cardiovascular risk locus 1p13.3, is a novel regulator of hepatic lipoprotein export. Cell Metab. 12, 213-223.

 

58. Klebe S, Thier S, Lorenz D, Nothnagel M, Schreiber S, Klein C, Hagenah J, Kasten M, Berg D, Srulijes K, Gasser T, Deuschl G, Kuhlenbäumer G (2010). LINGO1 is not associated with Parkinson’s disease in German patients. Am J Med Genet B Neuropsychiatr Genet. 153B (6), 1173-8.

 

59. Kleinhammer A, Wurst W, Kühn R (2010). Gene Knockdown in the Mouse through RNAi. Methods Enzymol. 477C, 387-414.

 

60. Kronenberg G, Gertz K, Cheung G, Buffo A, Kettenmann H, Götz M, Endres M (2010). Modulation of fate determinants Olig2 and Pax6 in resident glia evokes spiking neuroblasts in a model of mild brain ischemia. Stroke, 41 (12), 2944-9.

 

61. Liepelt I, Gaenslen A, Godau J, Di Santo A, Schweitzer KJ, Gasser T, Berg D (2010). Rivastigmine for the treatment of dementia in patients with progressive supranuclear palsy: Clinical observations as a basis for power calculations and safety analysis. Alzheimers Dement. 6 (1), 70-4.

 

62. Lücking CB, Lichtner P, Kramer ER, Gieger C, Illig T, Dichgans M, Berg D, Gasser T (2010). Polymorphisms in the receptor for GDNF (RET) are not associated with Parkinson's disease in Southern Germany. Neurobiol Aging 31 (1), 167-8.

 

63. Maetzler W, Schmid B, Synofzik M, Schulte C, Riester K, Huber H, Brockmann K, Gasser T, Berg D, Melms A (2010). The CST3 BB genotype and low cystatin C cerebrospinal fluid levels are associated with dementia in Lewy body disease. J Alzheimers Dis. 19 (3), 937-42.

 

64. Maetzler W, Schmid SP, Wurster I, Liepelt I, Gaenslen A, Gasser T, Berg D. (2010) Reduced but not oxidized cerebrospinal fluid glutathione levels are lowered in Lewy body diseases. Mov Disord. epub Sep 14.

 

65. Maetzler W, Stoycheva V, Schmid B, Schulte C, Hauser AK, Brockmann K, Melms A, Gasser T, Berg D (2010). Neprilysin Activity in Cerebrospinal Fluid is Associated with Dementia and Amyloid-β42 Levels in Lewy Body Disease. J Alzheimers Dis. 22 (3), 933-8.

 

66. Mbefo MK, Paleologou KE, Boucharaba A, Oueslati A, Schell H, Fournier M, Olschewski, D, Yin G, Zweckstetter M, Masliah E, Kahle PJ, Hirling, Lashuel H (2010). Phosphorylation of synucleins by members of the polo-like kinase family. J. Biol. Chem. 285, 2807-2822.

 

67. Meixner A, Boldt K, Van Troys M, Askenazi M, Gloeckner CJ, Bauer M, Marto JA, Ampe C, Kinkl N, Ueffing M (2010). A QUICK screen for Lrrk2 interaction partners leucine-rich repeat kinase 2 is involved in actin cytoskeleton dynamics. Mol Cell Proteomics. Sep 27 10(1), M110.001172.

 

68. Newbern J, Birchmeier C (2010). Nrg1/ErbB signaling networks in Schwann cell development and myelination. Semin Cell Dev Biol. 21 (9), 922-8.

 

69. Ninkovic J, Pinto L, Petricca S, Sun J, Rieger MA, Schroeder T, Cvekl A, Favor J and Götz M (2010) The transcription factor Pax6 regulates survival of dopaminergic olfactory bulb neurons via crystallin alphaA. Neuron, 68 (4), 682-94.

 

70. Novak M, Halbout B, O´Connor EC, Rodriguez Parkitna J, Su T, Chai M, Crombag HS, Bilbao A, Spanagel R, Stephens DN, Schütz G, Engblom D (2010). Incentive learning underlying cocaine-seeking requires mGluR5 receptors located on dopamine D1 receptor-expressing neurons. J. Neurosci. 30, 11973-11982.

 

71. O'Toole JF, Liu Y, Davis EE, Westlake CJ, Attanasio M, Otto EA, Seelow D, Nurnberg G, Becker C, Nuutinen M, Kärppä M, Ignatius J, Uusimaa J, Pakanen S, Jaakkola E, van den Heuvel LP, Fehrenbach H, Wiggins R, Goyal M, Zhou W, Wolf MT, Wise E, Helou J, Allen SJ, Murga-Zamalloa CA, Ashraf S, Chaki M, Heeringa S, Chernin G, Hoskins BE, Chaib H, Gleeson J, Kusakabe T, Suzuki T, Isaac RE, Quarmby LM, Tennant B, Fujioka H, Tuominen H, Hassinen I, Lohi H, van Houten JL, Rotig A, Sayer JA, Rolinski B, Freisinger P, Madhavan SM, Herzer M, Madignier F, Prokisch H, Nurnberg P, Jackson PK, Khanna H, Katsanis N, Hildebrandt F (2010). Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy. J Clin Invest. 120 (3), 791-802. Erratum in: J Clin Invest. 2010 120 (4),1362.

 

72. Palm C, Axer M, Gräßel D, Dammers J, Lindemeyer J, Zilles K, Pietrzyk U, Amunts K (2010). Towards ultra-high resolution fibre tract mapping of the human brain – Registration of polarised light images and reorientation of fibre vectors. Frontiers in Hum Neurosci., 4 (9): 1-16.

 

73. Pedro L, Padrós J, Beaudet L, Schubert HD, Gillardon F, Dahan S. (2010). Development of a high-throughput AlphaScreen assay measuring full-length LRRK2(G2019S) kinase activity using moesin protein substrate. Annal. Biochem. 404 (1), 45-51.

 

74. Pham TT, Giesert F, Röthig A, Floss T, Kallnik M, Weindl K, Hölter SM, Ahting U, Prokisch H, Becker L, Klopstock T, Hrabé de Angelis M, Beyer K, Görner K, Kahle PJ, Vogt Weisenhorn DM, Wurst W. (2010). DJ-1-deficient mice show less TH-positive neurons in the ventral tegmental area and exhibit non-motoric behavioural impairments. Genes Brain Behav.3, 305-17.

 

75. Piccoli G, Condliffe SB, Bauer M, Giesert F, Boldt K, De Astis S, Meixner A, Sarioglu H, Vogt-Weisenhorn DM, Wurst W, Gloeckner CJ, Matteoli M, Sala M, Ueffing M (2010). LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool, J. Neurosience, accepted

 

76. Reiche R, Theilig F, Rafiqi FH, Militz D, Mutig K, Todiras M, Christensen EI, Ellison DH, Bader M, Nykjaer A, Bachmann S, Alessi D, Willnow TE (2010). SORLA/SORL1 functionally interacts with SPAK to control renal activation of Na+-K+-Cl- cotransporter 2. Mol. Cell. Biol. 30, 3027-37.

 

77. Rosemann M, Ivashkevich A, Favor J, Dalke C, Hölter SM, Becker L, Racz I, Bolle I, Klempt M, Rathkolb B, Kalaydjiev S, Adler T, Aguilar A, Hans W, Horsch M, Rozman J, Calzada-Wack J, Kunder S, Gailus-Durner V, Fuchs H, Naton B, Schulz H, Beckers J, Busch DH, Burbach P, Smidt MP, Quintanilla-Fendt L, Esposito I, Klopstock T, Klingenspor M, Ollert M, Wolf E, Wurst W, Zimmer A, Hrabé de Angelis M, Atkinson M, Heinzmann U, Graw J. (2010). Microphthalmia, parkinsonism and enhanced nociception in Pitx3416insG mice. Mamm Genome 21(1-2), 13-27.

 

78. Schebelle L, Wolf C, Stribl C, Javaheri T, Schnütgen F, Ettinger A, Ivics Z, Hansen J, Ruiz P, von Melchner H, Wurst W, Floss T (2010). Efficient conditional and promoter-specific in vivo expression of cDNAs of choice by taking advantage of recombinase-mediated cassette exchange using FlEx gene traps. Nucleic Acids Res. 38 (9), e106. epub 2010 Feb 5.

 

79. Schmidt M, Trümbach D, Weber P, Wagner K, Scharf S, Liebl C, Datson N, Namendorf C, Gerlach T, Kühne C, Uhr M, Deussing J, Wurst W, Binder E, Holsboer F, Müller M. (2010). Individual stress vulnerability is predicted by short-term memory and AMPA receptor subunit ratio in the hippocampus. J. Neurosci. 30 (50), 16949-58.

 

80. Soehn AS, Franck T, Biskup S, Giaime E, Melle C, Rott R, Cebo D, Kalbacher H, Ott E, Pahnke J, Meitinger T, Kruger R, Gasser T, Berg D, von Eggeling F, Engelender S, da Costa CA, Riess O (2010). Periphilin is a novel interactor of synphilin-1, a protein implicated in Parkinson's disease. Neurogenetics.11 (2), 203-15.

 

81. Stuebner S, Faus-Kessler T, Fischer T, Wurst W, Prakash N (2010). Fzd3 and Fzd6 deficiency results in a severe midbrain morphogenesis defect. Dev Dyn. 239 (1), 246-60.

 

82. Südmeyer M, Pieperhoff P, Groiss S, Wojtecki L, Zilles K, Amunts K, Schnitzler A (2010). Spatio-temporal dynamics of brain volume changes in cortico-basal-degeneration. Movement Disorders (in press).

 

83. Trümbach D, Graf C, Pütz B, Kühne C, Panhuysen M, Weber P, Holsboer F, Wurst W, Welzl G, Deussing JM (2010). Deducing corticotropin-releasing hormone receptor type 1 signaling networks from gene expression data by usage of genetic algorithms and graphical Gaussian models. BMC Syst. Biol. 4, 159.

 

84. Tsolakidou A, Czibere L, Pütz B, Trümbach D, Panhuysen M, Deussing JM, Wurst W, Sillaber I, Landgraf R, Holsboer F, Rein T (2010). Gene expression profiling in the stress control brain region hypothalamic paraventricular nucleus reveals a novel gene network including amyloid beta precursor protein. BMC Genomics 11 (1), 546.

 

85. Vaegter CB, Jansen P, Fjorback AW, Glerup S, Skeldal S, Richner M, Erdmann B, Raarup MK, Nyengaard JR, Tessarollo L, Lewin GR, Willnow TE, Chao MV, Nykjaer A (2010). Sortilin anterogradely traffics Trk receptors and stimulate signaling by mature neurotrophins. Nat. Neurosci. 4 (1), 54-61.

 

86. von Wolff G, Avrabos C, Stepan J, Wurst W, Deussing JM, Holsboer F, Eder M (2011). Voltage-sensitive dye imaging demonstrates an enhancing effect of corticotropin-releasing hormone on neuronal activity propagation through the hippocampal formation. J. Psychiatr. Res. 45 (2), 256-61.

 

87. Walter M, Bonin M, Pullmann RS, Valente EM, Loi M, Gambarin M, Raymond D, Tinazzi M, Kamm C, Glöckle N, Poths S, Gasser T, Bressman SB, Klein C, Ozelius LJ, Riess O, Grundmann K (2010). Expression profiling in peripheral blood reveals signature for penetrance in DYT1 dystonia. Neurobiol Dis. 38 (2), 192-200.

 

88. Weiss D, Wächter T, Breit S, Jacob SN, Pomper JK, Asmus F, Valls-Solé J, Plewnia C, Gasser T, Gharabaghi A, Krüger R (2010). Involuntary eyelid closure after STN-DBS: evidence for different pathophysiological entities. J Neurol Neurosurg Psychiatry 81 (9), 1002-7.

 

89. Winklhofer, K. F., and C. Haass (2010). Mitochondrial dysfunction in Parkinson's disease. Biochimica et biophysica acta 1802, 29-44.

 

90. Zach S, Felk S, Gillardon F (2010). Signal transduction protein array analysis links LRRK2 to Ste20 kinases and PKC zeta that modulate neuronal plasticity. PLoS One. 5 (10), doi: 10.1371/journal.pone.0013191.

 

2009

1. Barnickel, T., Weston, J., Collobert, R., Mewes, H. W. & Stümpflen, V. (2009). Large scale application of neural network based semantic role labeling for automated relation extraction from biomedical texts. PLoS One 4, e6393, doi:10.1371/journal.pone.0006393.

 

2. Bauer, M., et al., (2009). Prevention of interferon-stimulated gene expression using microRNA-designed hairpins. Gene Ther. 16(1): p. 142-7.

 

3. Bieschke, J., Russ, J., Friedrich, R.P., Ehrnhoefer, D.E., Wobst, H., Neugebauer, K. and Wanker, E.E. (2009). EGCG remodels mature -synuclein and amyloid-β fibrils and reduces cellular toxicity. PNAS, doi/10.1073/pnas.0910723107.

 

4. Birchmeier, C. (2009). ErbB receptors and the development of the nervous system. Exp Cell Res,. 315(4): p. 611-8.

 

5. Brill, M. S. et al. (2009). Adult generation of glutamatergic olfactory bulb interneurons. Nat Neurosci 12, 1524-1533, doi:10.1038/nn.2416.

 

6. Chaurasia, G., et al., (2009). UniHI 4: new tools for query, analysis and visualization of the human protein-protein interactome. Nucleic Acids Res. 37(Database issue): p. D657-60.

 

7. Danek A, Diehl-Schmid J, Grimmer T, Laws SM, Neumann M, Perneczky R, Riemenschneider M, Kurz A, Förstl H. (2009). Frontotemporal lobar degeneration. Part 1: diagnosis and treatment. Fortschr Neurol Psychiatr.;77(3):169-76; quiz 177-9. [Epub 2009 Mar 12]

 

8. Di Benedetto, B., et al., (2009). Activation of ERK/MAPK in the lateral amygdala of the mouse is required for acquisition of a fear-potentiated startle response. Neuropsychopharmacology. 34(2): p. 356-66.

 

9. Di Benedetto, B., et al., (2009). Local knockdown of ERK2 in the adult mouse brain via adeno-associated virus-mediated RNA interference. Mol Biotechnol. 41(3): p. 263-9.

 

10. Dickson DW, Braak H, Duda JE, Duyckaerts C, Gasser T, Halliday GM, Hardy J, Leverenz JB, Del Tredici K, Wszolek ZK, Litvan I (2009). Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria. Lancet Neurol 8(12):1150-57.

 

11. Diehl-Schmid J, Neumann M, Laws SM, Perneczky R, Grimmer T, Danek A, Kurz A, Riemenschneider M, Förstl H. (2009). Frontotemporal lobar degeneration. Fortschr Neurol Psychiatr. 2009;77(5):295-304. [Epub 2009 Apr 1].

 

12. Djarmati A, Hagenah J, Reetz K, Winkler S, Behrens MI, Pawlack H, Lohmann K, Ramirez A, Tadic V, Bruggemann N, Berg D, Siebner HR, Lang AE, Pramstaller PP, Binkofski F, Kostic VS, Volkmann J, Gasser T, Klein C (2009). ATP13A2 variants in early-onset Parkinson's disease patients and controls. Movement Disord 24(14):2104-11.

 

13. Drzezga A, Grimmer T, Henriksen G, Mühlau M, Perneczky R, Miederer I, Praus C,Sorg C, Wohlschläger A, Riemenschneider M, Wester HJ, Foerstl H, Schwaiger M, Kurz A. (2009). Effect of APOE genotype on amyloid plaque load and gray matter volume in Alzheimer disease. Neurology. 72(17):1487-94. [Epub 2009 Apr 1].

 

14. Elstner M, Morris CM, Heim K, Lichtner P, Bender A, Mehta D, Schulte C, Sharma M, Hudson G, Goldwurm S, Giovanetti A, Zeviani M, Burn DJ, McKeith IG, Perry RH, Jaros E, Krüger R, Wichmann HE, Schreiber S, Campbell H, Wilson JF, Wright AF, Dunlop M, Pistis G, Toniolo D, Chinnery PF, Gasser T, Klopstock T, Meitinger T, Prokisch H, Turnbull DM. Single-cell expression profiling of dopaminergic neurons combined with association analysis identifies pyridoxal kinase as Parkinson's disease gene. Ann Neurol. 2009 Dec;66(6):792-8.

 

15. Fenzl T, Flachskamm C, Rossbauer M, Deussing JM, Kimura M (2009). Circadian rhythms of basal orexin levels in the hypothalamus are not influenced by an impaired corticotropin-releasing hormone receptor type 1 system. Behav Brain Res 203:143-145

 

16. Feulner TM, Laws SM, Friedrich P, Wagenpfeil S, Wurst SH, Riehle C, Kuhn KA, Krawczak M, Schreiber S, Nikolaus S, Förstl H, Kurz A, Riemenschneider M. (2009). Examination of the current top candidate genes for AD in a genome-wide association study. Mol Psychiatry.. [Epub ahead of print].

 

17. Friedrich P, Feulner TM, Laws SM, Eckart K, Perneczky R, Kurz A, Förstl H, Riemenschneider M. (2009). No association of Tachykinin receptor 2 (TACR2) polymorphisms with Alzheimer's disease. Neurobiol Aging. [Epub ahead of print].

 

18. Fuchs J, Mueller JC, Lichtner P, Schulte C, Munz M, Berg D, Wullner U, Illig T, Sharma M, Gasser T (2009). The transcription factor PITX3 is associated with sporadic Parkinson's disease. Neurobiol Aging 30(5):731-8.

 

19. Fuchs H, Gailus-Durner V, Lengger C, Naton B, Ferwagner B, Adler T, Aguilar Pimentel JA, Becker L, Bolle I, Brielmeier M, Calzada-Wack J, Ehrhardt N, Dalke C, Hans W, Hölter SM, Hölzlwimmer G, Horsch M, Javaheri A, Kallnik M, Kling E, Maier H, Moßbrugger I, Mörth C, Nöth U, Prehn C, Puk O, Radz I, Rathkolb B, Rozman J, Schäble K, Schreiner R, Schrewe A, Steinkamp R, Willershäuser M, Zeh R, Adamski J, Beckers J, Behrendt H, Busch DH, Esposito I, Favor J, Graw J, Heldmaier G, Höfler H, Ivandic B, Katus H, Klingenspor M, Klopstock T, Schughart K, Mempel M, Neschen S, Ollert M, Quintanilla-Martinez L, Schmidt J, Schulz H, Wolf E, Wurst W, Zimmer A, Hrabé de Angelis M. (2009). The German Mouse Clinic: A collaboration-based open access platform for systemic phenotype analysis of mouse models. Curr Pharm Biotechnol 10(2):236-243.

 

20. Gailus-Durner V, Fuchs H, Adler T, Aguilar Pimentel A, Becker L, Bolle I, Calzada-Wack J, Dalke C, Ehrhardt N, Ferwagner B, Hans W, Hölter SM, Hölzlwimmer G, Horsch M, Javaheri A, Kallnik M, Kling E, Lengger C, Mörth C, Mossbrugger I, Naton B, Prehn C, Puk O, Rathkolb B, Rozman J, Schrewe A, Thiele F, Adamski J, Aigner B, Behrendt H, Busch DH, Favor J, Graw J, Heldmaier G, Ivandic B, Katus H, Klingenspor M, Klopstock T, Ollert M, Quintanilla-Martinez L, Schulz H, Wolf E, Wurst W, Hrabé de Angelis M. (2009). Systemic first-line phenotyping. Methods Mol Biol 530:1-47.

 

21. Gillardon, F. (2009). Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability--a point of convergence in parkinsonian neurodegeneration? J Neurochem 110: 1514-22.

 

22. Gillardon, F., (2009). Interaction of elongation factor 1-alpha with leucine-rich repeat kinase 2 impairs kinase activity and microtubule bundling in vitro. Neuroscience 163:533-9.

 

23. Gloeckner, C.J., et al., (2009). The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7, in vitro. J Neurochem. 109(4). p: 959-68.

 

24. Goehler, H., Droege, A., Lurz, R., Schnoegl, S., Chernoff, Y. and Wanker, E. (2009). Pathogenic Polyglutamine Tracts Are Potent Inducers of Spontaneous Sup35 and Rnq1 Amyloidogenesis. PLoS ONE 5(3):e9642.

 

25. Golub Y, Berg D, Calne DB, Pfeiffer RF, Uitti RJ, Stoessl AJ, Wszolek ZK, Farrer MJ, Mueller JC, Gasser T, Fuchs J (2009). Genetic factors influencing age at onset in LRRK2-linked Parkinson disease. Parkinsonism Relat D 15(7):539-41.

 

26. Grimmer T, Riemenschneider M, Förstl H, Henriksen G, Klunk WE, Mathis CA, Shiga T, Wester HJ, Kurz A, Drzezga (2009). A. Beta amyloid in Alzheimer's disease: increased deposition in brain is reflected in reduced concentration in cerebrospinal fluid. Biol Psychiatry. 2009; 65(11):927-34. [Epub 2009 Mar 6].

 

27. Haslinger A, Schwarz TJ, Covic M, Chichung Lie D. (2009). Expression of Sox11 in adult neurogenic niches suggests a stage-specific role in adult neurogenesis. Eur J Neurosci. Jun;29(11):2103-14. Epub 2009 May 21.

 

28. Herbst, M., Bieschke, J., Schiele, F., Schmidt, M., Lurz, R., Wang, Q., Boeddrich, A., Kleckers, D., Wiglenda, T., Rautenberg, S., Friedrich, R., Otto, A., Anwyl, R., Schnoegl, S., Fändrich, M., Walsh, D. and Wanker, E. (2009). The natural compound orcein and related substances convert toxic amyloid-beta oligomers into non-toxic amyloid fibrils. Nat Chem Biol (submitted).

 

29. Hitz, C., et al., (2009). Generation of shRNA Transgenic Mice. Methods Mol Biol. 530: p. 1-29.

 

30. Jagasia R, Steib K, Englberger E, Herold S, Faus-Kessler T, Saxe M, Gage FH, Song H, Lie DC (2009). GABA-cAMP response element-binding protein signaling regulates maturation and survival of newly generated neurons in the adult hippocampus. J Neurosci. Jun 24;29(25):7966-77.

 

31. Jessberger, S., et al., (2009). Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats. Learn Mem. 16(2): p. 147-54.

 

32. Kamprath K, Plendl W, Marsicano G, Deussing JM, Wurst W, Lutz B, Wotjak CT (2009). Endocannabinoids mediate acute fear adaptation via glutamatergic neurons independently of corticotropin-releasing hormone signaling. Genes Brain Behav 8:203-211.

 

33. Klein CL, Rovelli G, Springer W, Schall C, Gasser T, Kahle PJ (2009). Homo- and heterodimerization of ROCO kinases: LRRK2 kinase inhibition by theLRRK2 ROCO fragment. J Neurochem 111(3):703-15.

 

34. Koch, A., et al., (2009). Proteasomal inhibition reduces parkin mRNA in PC12 and SH-SY5Y cells. Parkinsonism Relat Disord. 15(3): p. 220-5.

 

35. Laws SM, Eckart K, Friedrich P, Eisele T, Kurz A, Förstl H, Riemenschneider M. (2009). No association of lipase C polymorphisms with Alzheimer's disease. Neurobiol Aging. [Epub ahead of print].

 

36. Laws SM, Eckart K, Friedrich P, Kurz A, Förstl H, Riemenschneider M. Lack of evidence to support the association of polymorphisms within the alpha- and beta-secretase genes (ADAM10/BACE1) with Alzheimer's disease. Neurobiol Aging. 2009 [Epub ahead of print].

 

37. Liebl C, Panhuysen M, Putz B, Trumbach D, Wurst W, Deussing JM, Muller MB, Schmidt MV (2009). Gene expression profiling following maternal deprivation: involvement of the brain Renin-Angiotensin system. Front Mol Neurosci 2:1.

 

38. Lutz, A. K., N. Exner, M. E. Fett, J. S. Schlehe, K. Kloos, K. Lammermann, B. Brunner, A. Kurz-Drexler, F. Vogel, A. S. Reichert, L. Bouman, D. Vogt-Weisenhorn, W. Wurst, J. Tatzelt, C. Haass, and K. F. Winklhofer. (2009). Loss of parkin or PINK1 function increases DRP1-dependent mitochondrial fragmentation. J Biol Chem, doi:10.1074/jbc.M109.035774.

 

39. Madzar D, Schulte C, Gasser T (2009). Screening for LRRK2 R1441 mutations in a cohort of PSP patients from Germany. Eur J Neurol 16(11):1230-2.

 

40. Maetzler W, Keller S, Michelis J, Koehler N, Stransky E, Becker C, Schulte C, Melms A, Gasser T, Berg D (2009). No differences of butyrylcholinesterase protein activity and allele frequency in Lewy body diseases. Neurobiol Dis 35(2):296-301.

 

41. Maetzler W, Liepelt I, Reimold M, Reischl G, Solbach C, Becker C, Schulte C, Leyhe T, Keller S, Melms A, Gasser T, Berg D (2009). Cortical PIB binding in Lewy body disease is associated with Alzheimer-like characteristics. Neurobiol Dis 34(1):107-12.

 

42. Maetzler W, Michelis J, Tomiuk J, Melms A, Becker C, Gasser T, Schulte C, Berg D (2009). A single-nucleotide polymorphism of the osteopontin gene may contribute to a susceptibility to Lewy body disease. J Neural Transm 116(5):599-605.

 

43. Morais, V. A. et al. (2009). Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function. EMBO Mol Med 1(2), 99-111, doi:10.1002/emmm.200900006.

 

44. Rohe, M. et al. (2009). Brain-derived neurotrophic factor reduces amyloidogenic processing through control of SORLA gene expression. J Neurosci 29, 15472-15478, doi:10.1523/JNEUROSCI.3960-09.2009.

 

45. Palm, C., Vieten, A., Salber, D., Pietrzyk, U. (2009). Evaluation of registration strategies for multi-modality images of rat brain slices. Physics in Medicine and Biology, 54: 3269-3289.

 

46. Pichler S, Eckart K, Laws SM, Feulner TM, Friedrich P, Grimm HS, Grimm MO, Graff C, Wagenpfeil S, Riehle C, Eisele T, Müller J, Page RM, Haass C, Fakhri Björk B, Krawczak M, Schreiber S, Nikolaus S, Förstl H, Kurz A, Hartmann T, Mayhaus M, and Riemenschneider M. Common APP variants are associated with Alzheimer’s disease and cause alterations of gene expression and APP processing. (submitted)

 

47. Pinto, L., D. Drechsel, M.-T. Schmid, J. Ninkovic, M. Irmler, M.S. Brill, L. Restani, L. Gianfranceschi, C. Cerri, S.N. Weber, V. Tarabykin, F. Guillemot, J. Beckers, N. Zecevic, C. Dehay, M. Caleo, H. Schorle and M. Götz (2009). AP2γ regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex. Nature Neuroscience 12, 1229-1237.

 

48. Prinzen, C., D. Trümbach, et al. (2009). Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice. BMC Genomics 10: 66.

 

49. Robel, S., T. Mori, Z. Soubaa, J. Schlegel, S. Sirko, A. Faissner, S. Goebbels, L. Dimou and M. Götz (2009). Conditional deletion of b1 integrin in astroglia causes partial reactive gliosis. Glia 57, 1630-1647.

 

50. Rohe, M., M. Synowitz, Willnow, T., et al. (2009). "Brain-derived neurotrophic factor reduces amyloidogenic processing through control of SORLA gene expression." J Neurosci 29(49): 15472-8.

 

51. Schell, H., Hasegawa, T., Neumann, M., and Kahle, P. J. (2009). Nuclear and neuritic distribution of serine-129 phosphorylated a-synuclein in transgenic mice. Neuroscience 160, 796-804.

 

52. Schmidt MV, Sterlemann V, Wagner K, Niederleitner B, Ganea K, Liebl C, Deussing JM, Berger S, Schutz G, Holsboer F, Muller MB (2009). Postnatal glucocorticoid excess due to pituitary glucocorticoid receptor deficiency: differential short- and long-term consequences. Endocrinology 150:2709-2716.

 

53. Schmidt, T., Mewes, H. W. & Stumpflen, V. (2009). A novel putative miRNA target enhancer signal. PLoS One 4, e6473, doi:10.1371/journal.pone.0006473.

 

54. Scholz SW, Houlden H, Schulte C, Sharma M, Li A, Berg D, Melchers A, Paudel R, Gibbs JR, Simon-Sanchez J, Paisan-Ruiz C, Bras J, Ding J, Chen H, Traynor BJ, Arepalli S, Zonozi RR, Revesz T, Holton J, Wood N, Lees A, Oertel W, Wullner U, Goldwurm S, Pellecchia MT, Illig T, Riess O, Fernandez HH, Rodriguez RL, Okun MS, Poewe W, Wenning GK, Hardy JA, Singleton AB, Gasser T (2009). SNCA variants are associated with increased risk for multiple system atrophy. Ann Neurol 65(5):610-14

 

55. Schumacher A, Friedrich P, Diehl-Schmid J, Ibach B, Perneczky R, Eisele T, Vukovich R, Foerstl H, Riemenschneider M. (2009). No association of TDP-43 with sporadic frontotemporal dementia. Neurobiol Aging.;30(1):157-9. [Epub 2007 Jul 5].

 

56. Sharma M, Lichtner P, Kruger R, Berg D, Schulte C, Illig T, Riess O, Gasser T (2009). Further delineation of the association signal on chromosome 5 from the first whole genome association study in Parkinson's disease. Neurobiol Aging 30(10):1706-9.

 

57. Sidransky E, Nalls MA, Aasly JO, Aharon-Peretz J, Annesi G, Barbosa ER, Bar-Shira A, Berg D, Bras J, Brice A, Chen CM, Clark LN, Condroyer C, De Marco EV, Durr A, Eblan MJ, Fahn S, Farrer MJ, Fung HC, Gan-Or Z, Gasser T, Gershoni-Baruch R, Giladi N, Griffith A, Gurevich T, Januario C, Kropp P, Lang AE, Lee-Chen GJ, Lesage S, Marder K, Mata IF, Mirelman A, Mitsui J, Mizuta I, Nicoletti G, Oliveira C, Ottman R, Orr-Urtreger A, Pereira LV, Quattrone A, Rogaeva E, Rolfs A, Rosenbaum H, Rozenberg R, Samii A, Samaddar T, Schulte C, Sharma M, Singleton A, Spitz M, Tan EK, Tayebi N, Toda T, Troiano AR, Tsuji S, Wittstock M, Wolfsberg TG, Wu YR, Zabetian CP, Zhao Y, Ziegler SG (2009). Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease. New Engl J Med 361(17):1651-61.

 

58. Silberstein S, Vogl AM, Bonfiglio JJ, Wurst W, Holsboer F, Arzt E, Deussing JM, Refojo D (2009a). Immunology, signal transduction, and behavior in hypothalamic-pituitary-adrenal axis-related genetic mouse models. Ann N Y Acad Sci 1153:120-130.

 

59. Silberstein S, Vogl AM, Refojo D, Senin SA, Wurst W, Holsboer F, Deussing JM, Arzt E (2009b). Amygdaloid pERK1/2 in corticotropin-releasing hormone overexpressing mice under basal and acute stress conditions. Neuroscience 159:610-617.

 

60. Simon-Sanchez J, Schulte C, Bras JM, Sharma M, Gibbs JR, Berg D, Paisan-Ruiz C, Lichtner P, Scholz SW, Hernandez DG, Kruger R, Federoff M, Klein C, Goate A, Perlmutter J, Bonin M, Nalls MA, Illig T, Gieger C, Houlden H, Steffens M, Okun MS, Racette BA, Cookson MR, Foote KD, Fernandez HH, Traynor BJ, Schreiber S, Arepalli S, Zonozi R, Gwinn K, van der Brug M, Lopez G, Chanock SJ, Schatzkin A, Park Y, Hollenbeck A, Gao J, Huang X, Wood NW, Lorenz D, Deuschl G, Chen H, Riess O, Hardy JA, Singleton AB, Gasser T (2009). Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nat Genet 41(12):1308-12.

 

61. Spoelgen, R., et al., (2009). Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11. Neuroscience. 158(4): p. 1460-8.

 

62. Tamura, T., Sone, M., Yamashita, M., Wanker, E. and Okazawa, H. (2009). Glial cell lineage expression of mutant ataxin-1 and huntingtin induces developmental and late-onset neuronal pathologies in Drosophila models. PLoS ONE 4(1):e4262.

 

63. Uhrig M, Ittrich C, Wiedmann V, Knyazev Y, Weninger A, Riemenschneider M, Hartmann T. (2009). New Alzheimer amyloid beta responsive genes identified in human neuroblastoma cells by hierarchical clustering. PLoS One.26;4(8):e6779.

 

64. Vukovich R, Perneczky R, Drzezga A, Förstl H, Kurz A, Riemenschneider M. (2009). Brain metabolic correlates of cerebrospinal fluid beta-amyloid 42 and tau in Alzheimer's disease. Dement Geriatr Cogn Disord. 27(5):474-80. [Epub 2009 May 12].

 

65. Waak, J., Weber S.S., Waldenmaier A., Görner, K., Alunni-Fabbroni, M., Schell, H., Vogt Weisenhorn, D.M., Pham, T.T, Reumers, V., Baeklnadt V., Wurst, W., and P.J. Kahle (2009) Regulation of Astrocyte Inflammatory Responses by the Parkinson’s Disease-Associated Gene DJ-1. FASEB J. 23(8):2478-89.

 

66. Walter, M.C., et al., PEDANT covers all complete RefSeq genomes. Nucleic Acids Res, 2009. 37(Database issue): p. D408-11.

 

2008

1. Andersson, E.R., et al., Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivo. PLoS ONE, 2008. 3(10): p. e3517.

 

2. Birchmeier, C. and K.A. Nave, Neuregulin-1, a key axonal signal that drives Schwann cell growth and differentiation. Glia, 2008. 56(14): p. 1491-7.

 

3. Biskup, S., et al., Genes associated with Parkinson syndrome. J Neurol, 2008. 255 Suppl 5: p. 8-17.

 

4. Delic, S., et al., Genetic mouse models for behavioral analysis through transgenic RNAi technology. Genes Brain Behav, 2008. 7(7): p. 821-30.

 

5. Dimou, L., et al., Progeny of Olig2-expressing progenitors in the gray and white matter of the adult mouse cerebral cortex. J Neurosci, 2008. 28(41): p. 10434-42.

 

6. Dodson, S.E., et al., Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease. J Neurosci, 2008. 28(48): p. 12877-86.

 

7. Ehrnhoefer, DE, Bieschke, J, Boeddrich, A, Herbst, M, Masino, L, Lurz, R, Engemann, S, Pastore, A, Wanker EE. 2008. EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers. Nat. Struc. Mol. Biol 15: 558-566.

 

8. Golub, Y., et al., Genetic factors influencing age at onset in LRRK2-linked Parkinson disease. Parkinsonism Relat Disord, 2008.

 

9. Hanstein, R., et al., Transgenic overexpression of corticotropin releasing hormone provides partial protection against neurodegeneration in an in vivo model of acute excitotoxic stress. Neuroscience, 2008. 156(3): p. 712-21.

 

10. Klafke, R., W. Wurst, and N. Prakash, Genetic control of rodent midbrain dopaminergic neuron development in the light of human disease. Pharmacopsychiatry, 2008. 41 Suppl 1: p. S44-50.

 

11. Kronsbein, H.C., et al., CRHR1-dependent effects on protein expression and posttranslational modification in AtT-20 cells. Mol Cell Endocrinol, 2008. 292(1-2): p. 1-10.

 

12. Lu, A., et al., Conditional mouse mutants highlight mechanisms of corticotropin-releasing hormone effects on stress-coping behavior. Mol Psychiatry, 2008. 13(11): p. 1028-42.

 

13. O'Connor, T., et al., Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis. Neuron, 2008. 60(6): p. 988-1009.

 

14. Omodei, D., et al., Anterior-posterior graded response to Otx2 controls proliferation and differentiation of dopaminergic progenitors in the ventral mesencephalon. Development, 2008. 135(20): p. 3459-70.

 

15. Parlato, R., et al., Activation of an endogenous suicide response after perturbation of rRNA synthesis leads to neurodegeneration in mice. J Neurosci, 2008. 28(48): p. 12759-64.

 

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